At Café 21, it’s always happy hour! We’re serving up brunch, dinner and a complete line of craft cocktails every day of the week. As one of the most innovative restaurants in the Gaslamp District and University Heights, we’re committed to changing the way our customers think about food. If you’re looking for a delicious, gluten free & organic restaurant in San Diego, then you’ve come to the right place. As a champion of sustainable farming, we only use locally grown organic ingredients for a socially conscious farm-to-table dining experience. We use hormone-free meats and yeast-free bread to accommodate all dietary restrictions. We’ll even cater your next event, and provide the same level of service that you can expect at our restaurants. Experience live local music 7 days a week, a soothing atmosphere, and the best happy hour in downtown San Diego. It’s all happening right here at Café 21. Check out our centrally located, University Heights restaurant on Adams Avenue, for an intimate dining experience in a vibrant, emerging neighborhood. Call or click to make a reservation today!